CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-29b-3p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

TRAF5

Cancer information

Cancer name

Colorectal Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

14-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

34155879

Description

MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer

Tissue resource

human colorectal cancer cell lines HT-29

human colorectal cancer cell lines HCT-116

human colorectal cancer cell lines SW480

human colorectal cancer cell lines SW620

human colorectal cancer cell lines LoVo

human colorectal cancer cell lines SW48

human colorectal cancer cell lines DLD-1

human colorectal cancer cell lines Caco-1

human colorectal cancer cell lines HCT-15

Experiment

None

Institute

Country

Continent