HULC

ncRNA information

ncRNA name

HULC

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-137/ITGB8

Cancer information

Cancer name

Ovarian Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

28(<=50)+34(>50)

Age range and number

Not available

Research information

PMID

Description

Long noncoding RNA HULC contributes to paclitaxel resistance in ovarian cancer via miR-137/ITGB8 axis

Tissue resource

osteosarcoma tissues and adjacent normal tissues

human osteosarcoma cell lines SKOV3

human osteosarcoma cell lines HeyA-8

Experiment

62


Institute

Hubei General Hospital

Huiying

Country

China

China

Continent

Asia

Asia