CircMMP11

ncRNA information

ncRNA name

CircMMP11

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-153-3p/ANLN

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Lapatinib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Circular RNA circ-MMP11 Contributes to Lapatinib Resistance of Breast Cancer Cells by Regulating the miR-153-3p/ANLN Axis

Tissue resource

tissues samples from drug-resistant and drug-sensitive patients

normal human mammary epithelial cell lines MCF-10A

human breast cancer cell lines MDA-MB-231

human breast cancer cell lines MCF-7

Experiment

None


Institute

the Affilicated Huaian No.1 People’s Hospital of Nanjing Medical University

the Chinese Academy of Sciences Cell Bank

Country

China

China

Continent

Asia

Asia