Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircRNA_103615
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ABCB1
Cancer name
Non-Small Cell Lung Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
circRNA_103615 contributes to tumor progression and cisplatin resistance in NSCLC by regulating ABCB1
Tissue resource
non-small cell lung cancer tissue samples and adjacent non-cancerous tissue samples
human non-small cell lung cancer cell lines A549
human non-small cell lung cancer cell lines NCI-H1299
human non-small cell lung cancer cell lines H1650
human non-small cell lung cancer cell lines H358
normal lung cell lines Beas-2B
Experiment
None
Institute
Fuda Cancer Hospital
the Shanghai Cell Bank of the Chinese Academy of Sciences
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.