CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-222

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

p27Kip1

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Tamoxifen

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

18708351

Description

MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1.

Tissue resource

Experiment

qRT-PCR

Institute

Country

Continent