Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-27a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Esophageal Squamous Cell Carcinoma
Cancer site
Esophagus
Treatment type
Chemotherapy
Drug
5-Fluorouracil/Adriamycin/Cisplatin/Vincristine
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Down-Regulation of miR-27a Might Reverse Multidrug Resistance of Esophageal Squamous Cell Carcinoma.
Tissue resource
human esophageal squamous cell lines ECA109
human esophageal squamous cell lines TE-13
Experiment
qRT-PCR,Western blot,Northern blot,Luciferase reporter assay
Institute
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.