Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-342
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Tamoxifen
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Our clinical data indicates a trend towards reduced miR-342 expression and tamoxifen resistance.
Tissue resource
human primary breast tumors
human mammary carcinoma cell lines MCF-7
human breast cancer tamoxifen sensitive cell lines MCF-7/HER2
human breast cancer tamoxifen sensitive cell lines MCF-7/pcDNA
human breast cancer tamoxifenresistant cell lines MCF-7/HER2Δ16
Experiment
qRT-PCR,Northern blot
Institute
the University of Colorado
American Type Culture Collection
Country
USA
Continent
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.