hsa-miR-342

ncRNA information

ncRNA name

hsa-miR-342

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Tamoxifen

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Our clinical data indicates a trend towards reduced miR-342 expression and tamoxifen resistance.

Tissue resource

human primary breast tumors

human mammary carcinoma cell lines MCF-7

human breast cancer tamoxifen sensitive cell lines MCF-7/HER2

human breast cancer tamoxifen sensitive cell lines MCF-7/pcDNA

human breast cancer tamoxifenresistant cell lines MCF-7/HER2Δ16

Experiment

qRT-PCR,Northern blot


Institute

the University of Colorado

American Type Culture Collection

Country

USA

Continent

Amercia