Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircRERE
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-152-3p/CD47
Cancer name
Multiple Myeloma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Bortezomib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
CircRERE confers the resistance of multiple myeloma to bortezomib depending on the regulation of CD47 by exerting the sponge effect on miR-152-3p
Tissue resource
normal serum samples and serum patients from multiple myeloma patients
multiple myeloma cell lines 8226
multiple myeloma cell lines MM1.S
Experiment
None
Institute
the First Affiliated Hospital of Chongqing Medical University
BioVector NTCC Inc.
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.