CircRERE

ncRNA information

ncRNA name

CircRERE

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-152-3p/CD47

Cancer information

Cancer name

Multiple Myeloma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Bortezomib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

CircRERE confers the resistance of multiple myeloma to bortezomib depending on the regulation of CD47 by exerting the sponge effect on miR-152-3p

Tissue resource

normal serum samples and serum patients from multiple myeloma patients

multiple myeloma cell lines 8226

multiple myeloma cell lines MM1.S

Experiment

None


Institute

the First Affiliated Hospital of Chongqing Medical University

BioVector NTCC Inc.

Country

China

China

Continent

Asia

Asia