Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-200c
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Epirubicin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Up-regulation of miR-200c enhances the chemosensitivity to epirubicin and reduces MDR1 mRNA expression in breast cancer cells.
Tissue resource
breast cancer tissues
human breast cancer doxorubicin-resistant cell lines MCF-7/ADR
human breast cancer cell lines MCF-7
Experiment
qRT-PCR
Institute
Second Affiliated Hospital, School of Medicine Zhejiang University
Zhejiang University Cancer Institute
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.