hsa-miR-10b

ncRNA information

ncRNA name

hsa-miR-10b

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Colorectal Cancer

Cancer site

Colon, Rectum, and Anus

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The overexpression of miR-10b confers chemoresistance in colorectal cancer cells to 5-FU.

Tissue resource

colorectal cancer tissues and normal tissues

human colorectal cancer cell lines HCT-116

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Kyushu University Hospital at Beppu and affiliated hospitals

American Type Culture Collection

Country

Japan

USA

Continent

Asia

Amercia