hsa-miR-181a

ncRNA information

ncRNA name

hsa-miR-181a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

PRKCD

Cancer information

Cancer name

Cervical Cancer

Cancer site

Cervix Uteri

Treatment information

Treatment type

Radiotherapy

Impact of wild-type ncRNA on radiotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Higher expression of miR-181a was observed in human cervical cancer specimens and cell lines that were insensitive to radiation therapy, as compared with sensitive cancer specimens and the cell lines.

Tissue resource

tumor specimens from squamous cervical carcinoma

human cervical cancer cell lines SiHa

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Shanghai Cancer Center, Fudan University

Country

China

Continent

Asia