Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-200c
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
BMI-1
Cancer name
Melanoma
Cancer site
Skin
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-200c Inhibits Melanoma Progression and Drug Resistance through Down-Regulation of Bmi-1.
Tissue resource
melanomas tissues
human melanoma cell lines WM35
human melanoma cell lines WM793
human melanoma cell lines WM115A
human melanoma cell lines WM3523A
human melanoma cell lines 1205Lu
human embryonic kidney cell lines HEK-293T
Experiment
qRT-PCR,Western blot
Institute
Hospital of the University of Pennsylvania
The Wistar Institute
Country
USA
Continent
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.