hsa-miR-30c

ncRNA information

ncRNA name

hsa-miR-30c

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factors

Not available

Downstream target

TWF1/IL-11

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin/Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

23340433

Description

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.

Tissue resource

breast tumour tissues

human breast cancer cell lines MCF7

human embryonic kidney cell lines HEK-293T

Experiment

qRT-PCR,Western blot,Luciferase reporter assay

Institute

University of Chicago

Country

USA

Continent

Amercia

Institutes for Systems Genetics, West China Hospital
     Copyright @ 2022 ISG. All Rights Reserved.