Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-31
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Ovarian Cancer
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Re-introduction of miR31 re-sensitized them to PTX both in vitro and in vivo.
Tissue resource
ovarian cancer specimens
human ovarian cancer cell lines KF
human ovarian cancer cisplatin-resistant cell lines KFr13
human ovarian cancer cell lines RMG-1
human ovarian cancer cell lines TU-OM-1
human ovarian cancer cell lines SK-OV-3
human ovarian cancer cell lines OVCAR-3
Experiment
qRT-PCR,Luciferase reporter assay
Institute
Hokkaido University Hospital
National Defense Medical College
Health Science Research Resources Bank
Tottori University School of Medicine
American Type Culture Collection
Country
Japan
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.