hsa-miR-31

ncRNA information

ncRNA name

hsa-miR-31

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Ovarian Cancer

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Re-introduction of miR31 re-sensitized them to PTX both in vitro and in vivo.

Tissue resource

ovarian cancer specimens

human ovarian cancer cell lines KF

human ovarian cancer cisplatin-resistant cell lines KFr13

human ovarian cancer cell lines RMG-1

human ovarian cancer cell lines TU-OM-1

human ovarian cancer cell lines SK-OV-3

human ovarian cancer cell lines OVCAR-3

Experiment

qRT-PCR,Luciferase reporter assay


Institute

Hokkaido University Hospital

National Defense Medical College

Health Science Research Resources Bank

Tottori University School of Medicine

American Type Culture Collection

Country

Japan

USA

Continent

Asia

Amercia