hsa-miR-375

ncRNA information

ncRNA name

hsa-miR-375

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Cervical Cancer

Cancer site

Cervix Uteri

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Forced overexpression of miR-375 in cervical cancer cells decreased paclitaxel sensitivity in vitro and in vivo.

Tissue resource

cervical squamous cell carcinoma tissues

human cervical cancer cell lines SiHa

human cervical cancer cell lines Caski

Experiment

qRT-PCR


Institute

School of Medicine, Zhejiang University

American Type Culture Collection

Country

China

USA

Continent

Asia

Amercia