Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-320c
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
SMARCC1
Cancer name
Pancreatic Cancer
Cancer site
Pancreas
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-320c inhibits the response to gemcitabine by targeting SMARCC1.
Tissue resource
pancreatic cancer tissues
human pancreatic carcinoma cell lines MiaPaCa2
human pancreatic carcinoma cell lines PSN-1
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
Graduate School of Medicine, Osaka University
the Japanese Collection of Research Bioresources
Country
Japan
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.