Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-29a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Wnt/Ī²-catenin signaling pathway
Cancer name
Pancreatic Cancer
Cancer site
Pancreas
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MicroRNA-29a induces resistance to gemcitabine through the Wnt/Ī²-catenin signaling pathway in pancreatic cancer cells.
Tissue resource
human pancreatic carcinoma cell lines MIAPaCa-2
human pancreatic carcinoma cell lines PSN-1
human pancreatic carcinoma cell lines BxPC-3
human pancreatic carcinoma cell lines Panc-1
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
the Japanese Collection of Research Bioresources
American Type Culture Collection
Country
Japan
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.