hsa-miR-29a

ncRNA information

ncRNA name

hsa-miR-29a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Wnt/Ī²-catenin signaling pathway

Cancer information

Cancer name

Pancreatic Cancer

Cancer site

Pancreas

Treatment information

Treatment type

Chemotherapy

Drug

Gemcitabine

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-29a induces resistance to gemcitabine through the Wnt/Ī²-catenin signaling pathway in pancreatic cancer cells.

Tissue resource

human pancreatic carcinoma cell lines MIAPaCa-2

human pancreatic carcinoma cell lines PSN-1

human pancreatic carcinoma cell lines BxPC-3

human pancreatic carcinoma cell lines Panc-1

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the Japanese Collection of Research Bioresources

American Type Culture Collection

Country

Japan

USA

Continent

Asia

Amercia