hsa-miR-106a

ncRNA information

ncRNA name

hsa-miR-106a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

RUNX3

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin/5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

These findings demonstrate that miR-106a may promote MDR in GC cells by targeting RUNX3.

Tissue resource

human gastric adenocarcinoma cell lines SGC7901

Experiment

qRT-PCR,Western blot


Institute

Academy of Military Medical Science

Country

China

Continent

Asia