hsa-miR-320a

ncRNA information

ncRNA name

hsa-miR-320a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Gastrointestinal Stromal Tumor

Cancer site

Stomach, Small Intestine

Treatment information

Treatment type

Chemotherapy

Drug

Imatinib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Up

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Downregulation of miR-320a in GISTs could be responsible for the tumor acquiring drug-resistant potential, resulting in imatinib resistance.

Tissue resource

gastrointestinal stromal tumors tissues

Experiment

qRT-PCR


Institute

Zhongshan Hospital, Fudan University

Country

China

Continent

Asia