Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-98
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ABCC10/MRP-7
Cancer name
Endometrial Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
30
Male patients
30
Female patients
Not available
Age range and number
Not available
PMID
Description
downregulation of miR-98 have important roles in conferring paclitaxel resistance to EC cells
Tissue resource
fresh endometrial cancer samples and paired normal tissue samples
human endometrial cancer cell lines RL95
human endometrial cancer cell lines HEC-1
human normal endometrial fibroblast cell lines HESC
human normal endometrial fibroblast cell lines HEK293
Experiment
60
Institute
Hubei Cancer Hospital of Tongji Medical College of Huazhong University of Science and Technology
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.