Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-200b
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ZEB2
Cancer name
Small Cell Lung Cancer
Cancer site
Lung
Treatment type
Chemotherapy
Drug
Adriamycin/Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Up-regulation of miR-200b sensitized cells to anticancer drugs.
Tissue resource
small cell lung cancer samples
human small cell lung cancer cell lines NCI-H69
human small cell lung cancer drugresistant sublines H69AR
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
the SouthernMedical University
American Type Culture Collection
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.