hsa-miR-200b

ncRNA information

ncRNA name

hsa-miR-200b

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

ZEB2

Cancer information

Cancer name

Small Cell Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin/Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Up-regulation of miR-200b sensitized cells to anticancer drugs.

Tissue resource

small cell lung cancer samples

human small cell lung cancer cell lines NCI-H69

human small cell lung cancer drugresistant sublines H69AR

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the SouthernMedical University

American Type Culture Collection

Country

China

USA

Continent

Asia

Amercia