Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-34a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
HDAC1/HDAC7
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Immunotherapy
Treatment name
Impact of wild-type ncRNA on resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-34a regulates therapy resistance by targeting HDAC1 and HDAC7 in breast cancer.
Tissue resource
breast cancer cell lines MCF-7
breast cancer cell lines MDA-MB-231
breast cancer cell lines BT-20
breast cancer cell lines T47-D
breast cancer cell lines PC3
breast cancer cell lines DU-145
breast cancer cell lines LNCaP
breast cancer cell lines NIH:OVCAR
breast cancer cell lines SK-OV-3
breast cancer cell lines HeLa
non-transformed mammary cell lines MCF-10A
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
American Type Culture Collection
Country
USA
Continent
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.