hsa-miR-34a

ncRNA information

ncRNA name

hsa-miR-34a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

HDAC1/HDAC7

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Immunotherapy

Treatment name

Impact of wild-type ncRNA on resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-34a regulates therapy resistance by targeting HDAC1 and HDAC7 in breast cancer.

Tissue resource

breast cancer cell lines MCF-7

breast cancer cell lines MDA-MB-231

breast cancer cell lines BT-20

breast cancer cell lines T47-D

breast cancer cell lines PC3

breast cancer cell lines DU-145

breast cancer cell lines LNCaP

breast cancer cell lines NIH:OVCAR

breast cancer cell lines SK-OV-3

breast cancer cell lines HeLa

non-transformed mammary cell lines MCF-10A

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

American Type Culture Collection

Country

USA

Continent

Amercia