hsa-miR-24-3p

ncRNA information

ncRNA name

hsa-miR-24-3p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

ATG4A

Cancer information

Cancer name

Small Cell Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin/Etoposide

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Overexpression of miR-24-3p into H446/EP cells led to reduction of the ATG4A protein level, allowing SCLC cells to resensitize to VP16ā€“DDP.

Tissue resource

human small-cell lung carcinoma cell lines H446

human small-cell lung carcinoma cell lines LTEP

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

the Tumor Cell Bank of the Chinese Academy of Medical Science

Country

China

Continent

Asia