hsa-miR-301a

ncRNA information

ncRNA name

hsa-miR-301a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

AMPKĪ±1/HMGCR

Cancer information

Cancer name

Osteosarcoma

Cancer site

Bone, Articular Cartilage

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Up-regulation of miR-301a contributed to chemoresistance of OS cells.

Tissue resource

human osteosarcoma specimens

human osteosarcoma cell lines U2OS

human osteosarcoma cell lines MG-63

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Tianjin Medical University

American Type Culture Collection

Country

China

USA

Continent

Asia

Amercia