hsa-miR-1323

ncRNA information

ncRNA name

hsa-miR-1323

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

PRKDC

Cancer information

Cancer name

Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Radiotherapy

Impact of wild-type ncRNA on radiotherapy resistance

Knockdown of microRNA-1323 restores sensitivity to radiation

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Inhibition of miR-1323 reversed the radioresistance of cancer cells and subsequently suppressed the expression of miR-1323-regulated DNA-PKcs protein.

Tissue resource

human lung cancer cell lines A549

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

American Type Culture Collection

Country

USA

Continent

Amercia