CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-141

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Keap1

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

Liver

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

25896253

Description

MiR-141 confers HCC cells resistance against 5-fluorouracil.

Tissue resource

human hepatocellular carcinoma cell lines HepG2

human hepatocellular carcinoma cell lines SMMC-7721

human hepatocellular carcinoma cell lines HuH7

Experiment

qRT-PCR,Western blot

Institute

the China Military Medical Science Academy of the PLA

Country

China

Continent

Asia