hsa-miR-218

ncRNA information

ncRNA name

hsa-miR-218

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin/Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Ectopic expression of miR-218 resensitized both drug resistant cell lines to doxorubicin and taxol due to an increase in apoptosis.

Tissue resource

human breast cancer cell lines MCF-7

human breast cancer cell lines Cal51

human breast cancer drug resistant cell lines MCF-7/ADR

human breast cancer drug resistant cell lines CALDOX

Experiment

qRT-PCR,Western blot


Institute

Country

Continent