Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
GAS5
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Lung Adenocarcinoma
Cancer site
Lung
Treatment type
Chemotherapy
Drug
Gefitinib
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Down
Number of patients
72
Male patients
37
Female patients
35
Age range and number
Not available
PMID
Description
GAS5 treatment enhances gefitinib sensitivity in vitro.
Tissue resource
paired cancerous and matched adjacent noncancerous lung tissues
human lung adenocarcinoma cell lines A549
human lung adenocarcinoma cell lines H1299
human lung adenocarcinoma cell lines H1975
human lung adenocarcinoma cell lines HCC827
human lung adenocarcinoma cell lines HBE
Experiment
qRT-PCR,Western blot
Institute
First Hospital of China Medical University
the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.