hsa-miR-20a

ncRNA information

ncRNA name

hsa-miR-20a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

LRIG1

Cancer information

Cancer name

Glioblastoma

Cancer site

Brain, Central Nervous System

Treatment information

Treatment type

Chemotherapy

Drug

Temozolomide

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Overexpression of miR-20a by treatment with miR-20a mimic resulted in increased TMZ resistance.

Tissue resource

human glioma cell lines U251

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the Cell Bank of the Chinese Academy of Sciences

Country

China

Continent

Asia