UCA1

ncRNA information

ncRNA name

UCA1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

SRPK1

Cancer information

Cancer name

Ovarian Cancer

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

UCA1 RNA in SKOV3 cells enhanced the cell migration, invasion and cisplatin resistance.

Tissue resource

ovarian tumor specimens

human ovarian cancer cell lines SKOV3

Experiment

qRT-PCR,Western blot


Institute

People's Hospital of Shaanxi Providence

Country

China

Continent

Asia