hsa-miR-150

ncRNA information

ncRNA name

hsa-miR-150

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

PI3K-Akt signaling pathway

Cancer information

Cancer name

Ovarian Cancer

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Pertuzumab

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Up

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiRNA-150 downregulation promotes pertuzumab resistance in ovarian cancer cells via AKT activation.

Tissue resource

ovarian cancer cell lines SKOV3

ovarian cancer cell lines SNU119

Experiment

qRT-PCR,Western blot


Institute

Type Culture Collection of Chinese Academy of Sciences

Country

China

Continent

Asia