MEG3

ncRNA information

ncRNA name

MEG3

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

p53/Bcl-xl

Cancer information

Cancer name

Lung Adenocarcinoma

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma.

Tissue resource

lung adenocarcinoma tissues

human lung adenocarcinoma cell lines A549

Experiment

qRT-PCR,Western blot


Institute

the First Affiliated Hospital of Nanjing Medical University/the Second Affiliated Hospital of Nanjing Medical University

the Cancer Institute, Chinese Academy of Sciences

Country

China

Continent

Asia