Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-130a
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Ovarian Cancer
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-130a and miR-374a mimics decreased the sensitivity of A2780 cells to cisplatin.
Tissue resource
human ovarian cancer cell lines A2780
human ovarian cancer cisplatin-resistant sublines A2780/DDP
human ovarian cancer cell lines A2780
human ovarian cancer cisplatin-resistant sublines A2780/DDP
Experiment
qRT-PCR,Western blot
Institute
West China Second University Hospital, Sichuan University
West China Second University Hospital, Sichuan University
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.