hsa-miR-522

ncRNA information

ncRNA name

hsa-miR-522

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

ABCB5

Cancer information

Cancer name

Colon Cancer

Cancer site

Colon, Rectum, and Anus

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MicroRNA-522 reverses drug resistance of doxorubicin-induced HT29 colon cancer cell by targeting ABCB5.

Tissue resource

human colon cancer cell lines HT29

Experiment

qRT-PCR,Western blot


Institute

American Type Culture Collection

Country

USA

Continent

Amercia