hsa-miR-218

ncRNA information

ncRNA name

hsa-miR-218

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

SMO

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin/Oxaliplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Down

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

These findings suggest that miR-218 inhibits MDR of gastric cancer cells by down-regulating SMO expression.

Tissue resource

human gastric adenocarcinoma cell lines SGC7901

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Guangzhou Medical University

Country

China

Continent

Asia