hsa-miR-20a

ncRNA information

ncRNA name

hsa-miR-20a

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

NFKBIB

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-20a enhances cisplatin resistance of human gastric cancer cell line by targeting NFKBIB.

Tissue resource

gastric cancer samples

human gastric cancer cell lines SGC7901

human gastric cancer cisplatin-resistant cell lines SGC7901/DDP

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

the First Affiliated Hospital of Nanjing Medical University

National Institute of Cells

KeyGEN Biotechnology Company

Country

China

Continent

Asia