HOTAIR

ncRNA information

ncRNA name

HOTAIR

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Tamoxifen

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer.

Tissue resource

breast cancer tissue specimens

Experiment

qRT-PCR,Western blot


Institute

the Cancer Center of Guangzhou Medical University

Country

China

Continent

Asia