Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-24
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
PTEN/Akt signaling pathway
Cancer name
Tongue Squamous Cell Carcinoma
Cancer site
Tongue
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-24 induces cisplatin resistance through targeting PTEN in TSCC cells.
Tissue resource
pairs of tongue squamous cell carcinoma and adjacent normal tissues
non-tumorigenic cell lines NHOK
tongue squamous cell carcinoma cell lines UM1
tongue squamous cell carcinoma cell lines UM2
tongue squamous cell carcinoma cell lines Ca127
tongue squamous cell carcinoma cell lines SCC1
tongue squamous cell carcinoma cell lines SCC2
tongue squamous cell carcinoma cell lines SCC9
tongue squamous cell carcinoma cell lines SCC15
tongue squamous cell carcinoma cell lines SCC25
Experiment
qRT-PCR,Western blot
Institute
Tianjin Cancer Hospital and Institute
American Type Culture Collection
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.