Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
ODRUL
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Osteosarcoma
Cancer site
Bone, Articular Cartilage
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
60
Male patients
46
Female patients
14
Age range and number
Not available
PMID
Description
LncRNA ODRUL contributes to doxorubicin resistance of osteosarcoma.
Tissue resource
primary osteosarcoma tissues
human osteosarcoma cell lines MG63
human osteosarcoma cell lines SaoS2
human osteosarcoma cell lines U-2OS
Experiment
qRT-PCR,Western blot
Institute
Shanghai Tenth People's Hospital
American Type Culture Collection
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.