hsa-miR-634

ncRNA information

ncRNA name

hsa-miR-634

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

Ras-MAPK

Cancer information

Cancer name

Ovarian Cancer

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.

Tissue resource

bladder carcinoma cell lines T24

colon carcinoma cell lines HCT8

ovarian cancer cell lines A2780

ovarian cancer cell lines OV56

ovarian cancer cell lines OAW42

ovarian cancer cell lines TOV112D

ovarian cancer cell lines TOV21G

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the European Collection of Authenticated Cell Cultures

American Type Culture Collection

Country

UK

USA

Continent

Europe

Amercia