Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-634
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Ras-MAPK
Cancer name
Ovarian Cancer
Cancer site
Ovary
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.
Tissue resource
bladder carcinoma cell lines T24
colon carcinoma cell lines HCT8
ovarian cancer cell lines A2780
ovarian cancer cell lines OV56
ovarian cancer cell lines OAW42
ovarian cancer cell lines TOV112D
ovarian cancer cell lines TOV21G
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
the European Collection of Authenticated Cell Cultures
American Type Culture Collection
Country
UK
USA
Continent
Europe
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.