hsa-miR-155

ncRNA information

ncRNA name

hsa-miR-155

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Suppression of miR-155 in this cell line considerably reversed doxorubicin resistance.

Tissue resource

non-small cell lung cancer cell lines A549

non-small cell lung cancer doxorubicin-resistant cell lines A549/dox

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

American Type Culture Collection

Country

USA

Continent

Amercia