Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
GAS5
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Prognosis/Treatment
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Trastuzumab
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer.
Tissue resource
human breast cancer specimens
human breast cancer cell lines SKBR-3
Experiment
qRT-PCR,Western blot
Institute
the Affiliated Hospital of Weifang Medical University
the Chinese Type Culture Collection, Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.