hsa-miR-363

ncRNA information

ncRNA name

hsa-miR-363

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

FBW7

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil/Cisplatin/Docetaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-363 promotes proliferation and chemo-resistance of human gastric cancer via targeting of FBW7 ubiquitin ligase expression.

Tissue resource

human gastric cancer tissues and adjacent normal tissues

human gastric cancer cell lines HGC-27

human gastric cancer cell lines MGC-803

human gastric cancer cell lines SGC-7901

human gastric cancer cell lines BGC-823

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

the Shanghai Jiao Tong University Affiliated Sixth People's Hospital

the Cell Bank, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

Country

China

Continent

Asia