MALAT1

ncRNA information

ncRNA name

MALAT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-216b

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

Liver

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The results showed that MALAT1 was over two times higher in BEL-7402/5-FU cells than in BEL-7402 cells.

Tissue resource

human hepatocellular carcinoma cell lines BEL-7402

human hepatocellular carcinoma multidrug-resistant cell lines BEL-7402/5-FU

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

Shanghai Meixuan Biological Technology Co., Ltd.

Country

China

Continent

Asia