LINC00152

ncRNA information

ncRNA name

LINC00152

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-193a-3p/ERBB4/AKT signaling pathway

Cancer information

Cancer name

Colon Cancer

Cancer site

Colon, Rectum, and Anus

Treatment information

Treatment type

Chemotherapy

Drug

Oxaliplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance.

Tissue resource

colon cancer tissues and paired adjacent normal mucosa

human colon mucosal epithelial cell lines NCM460

colon cancer cell lines SW480

colon cancer cell lines Caco2

colon cancer cell lines SW620

colon cancer cell lines HT29

Experiment

qRT-PCR,Western blot


Institute

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Country

China

Continent

Asia