Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LINC00152
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-193a-3p/ERBB4/AKT signaling pathway
Cancer name
Colon Cancer
Cancer site
Colon, Rectum, and Anus
Treatment type
Chemotherapy
Drug
Oxaliplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance.
Tissue resource
colon cancer tissues and paired adjacent normal mucosa
human colon mucosal epithelial cell lines NCM460
colon cancer cell lines SW480
colon cancer cell lines Caco2
colon cancer cell lines SW620
colon cancer cell lines HT29
Experiment
qRT-PCR,Western blot
Institute
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.