hsa-miR-193a-5p

ncRNA information

ncRNA name

hsa-miR-193a-5p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Upstream regulatory factors

Not available

Downstream target

TFAP2A

Cancer information

Cancer name

Bladder Cancer

Cancer site

Bladder

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

While knockdown of AP-2Ī± gene or overexpression of miR-193a-5p in the urothelial cell line SV-HUC-1 increased migration and cisplatin resistances.

Tissue resource

human embryonic kidney cell lines HEK-293T

human urothelial cell lines SV-HUC-1

bladder cancer lines UM-UC-3

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

American Type Culture Collection

Country

USA

Continent

Amercia