Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-425-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
SIRT1
Cancer name
Liver Cancer
Cancer site
None
Treatment type
Chemotherapy
Drug
Sorafenib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
miR-425 regulates lipophagy via SIRT1 to promote sorafenib resistance in liver cance
Tissue resource
lung cancer cell lines HepG2
lung cancer cell lines Hep3B
lung cancer cell lines PLC
lung cancer cell lines MIHA
Experiment
None
Institute
CoBioer Biosciences Co Ltd
Hunan Fenghui Biotechnology Co Ltd
Country
Continent
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.