CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-375

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

SEC23A/YAP1

Cancer information

Cancer name

Prostate Cancer

Cancer site

Prostate

Treatment information

Treatment type

Chemotherapy

Drug

Docetaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

27832783

Description

MiR-375 contributes to docetaxel resistance in PC cell lines.

Tissue resource

human prostate cancer cell lines DU145

human prostate cancer cell lines PC-3

Experiment

qRT-PCR,Western blot

Institute

American Type Culture Collection

Country

USA

Continent

Amercia