Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
SRLR
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Prognosis/Treatment
Upstream regulatory factors
Not available
Downstream target
IL-6/STAT3
Cancer name
Renal Cell Carcinoma
Cancer site
Kidney
Treatment type
Chemotherapy
Drug
Sorafenib
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LncRNA-SRLR knockdown sensitized nonresponsive RCC cells to sorafenib treatment.
Tissue resource
sorafenib-treated and nonsorafenib-treated paired renal cell carcinoma tissues
Experiment
qRT-PCR
Institute
Changhai Hospital
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.