SRLR

ncRNA information

ncRNA name

SRLR

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Prognosis/Treatment

Upstream regulatory factors

Not available

Downstream target

IL-6/STAT3

Cancer information

Cancer name

Renal Cell Carcinoma

Cancer site

Kidney

Treatment information

Treatment type

Chemotherapy

Drug

Sorafenib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA-SRLR knockdown sensitized nonresponsive RCC cells to sorafenib treatment.

Tissue resource

sorafenib-treated and nonsorafenib-treated paired renal cell carcinoma tissues

Experiment

qRT-PCR


Institute

Changhai Hospital

Country

China

Continent

Asia