UCA1

ncRNA information

ncRNA name

UCA1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-16

Cancer information

Cancer name

Chronic Myeloid Leukemia

Cancer site

Leukemia

Treatment information

Treatment type

Chemotherapy

Drug

Imatinib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA UCA1 Contributes to Imatinib Resistance by Acting as a ceRNA Against miR-16 in Chronic Myeloid Leukemia Cells.

Tissue resource

human chronic myeloid leukemia cell line K562

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

Cell Bank of Chinese Academy of Sciences

Country

China

Continent

Asia